NIRSBOX

We offer a Time-Domain Near Infrared Spectroscopy solution

  • Measures the absolute value of local oxy-, deoxy- and total hemoglobin concentration changes and tissue saturation index (TSI).

  • Compact and truly portable TD-NIRS device.

  • Possibility to operate without being connected to a power plug using an internal battery pack.

  • Offers real-time measurements with a high sampling rate (up to 50 Hz using the fast TD-NIRS option).  

  • A variety of optical probes are available to ensure the perfect fit for your application.

Compact & dual-wavelength TD-NIRS device

The NIRSBOX is a portable, dual-wavelength, Time-Domain NIRS system designed to investigate and monitor optical properties in biological tissue. It utilizes picosecond laser pulses and single-photon detection to provide precise measurements. With its dual-wavelength single-channel probe, the NIRSBOX measures absolute values of local oxyhemoglobin, deoxyhemoglobin, total hemoglobin concentrations and provides you with the tissue saturation index (TSI).

Weighing approximately 3 kilograms and measuring 20 x 12 x 24.5 centimeters, the NIRSBOX offers the full capabilities of TD-NIRS in a compact, portable form. This makes it easy to transport for studies involving multiple subjects at different locations. The NIRSBOX is delivered as a plug-and-play solution and is compatible with various probes to suit your research needs. Its user-friendly design eliminates the need for a specialized technician. For enhanced portability, we offer a rolling table and tablet configuration. The device also features an internal battery pack, allowing operation without a constant power supply.

Key strengths of the NIRSBOX include minimal warm-up time, high precision, and exceptional measurement stability:

  • Good Reproducibility: Less than 2% variation over one month on tissue-mimicking phantoms.

  • Remarkably Stable: Less than 1% variation over 14+ hours of continuous measurement.

  • Highly precise: Verified through the MEDPHOT assessment protocol for Diffuse Optics devices.

NIRSBOX Features

  • Analog Output Signals: Provides signals proportional to physiological parameters for easy interpretation and analysis.

  • Flexible External Triggering: Offers robust external triggering capabilities for synchronized data collection.

  • Event Marking: Enables the addition of events to your data stream, facilitating detailed analysis.

  • Real-Time Measurement: Supports high sampling rates (up to 50 Hz with the fast TD-NIRS option) for accurate, real-time data acquisition.

  • Lab Integration: Designed for seamless integration into various laboratory environments.

  • Durable and Replaceable Optical Probes: Features rugged, easily replaceable optical probes to ensure long-term reliability and convenience.

APPLICATIONS

  • Hemodynamic monitoring of brain and muscle tissue

  • Brain functional activation measurements

  • Optical non-invasive characterization of diffusive media

  • Quality assessment of food and vegetables

Probes variety

We offer a selections of probes to fit your research participants needs.

G5 "Goccia" optical probe

The G5 optode is waterproof, flexible, and durable, designed with adaptive geometry for curved surfaces and enhanced ambient light rejection. This advanced probe features a built-in contact sensor and comes equipped with a smart IRFBOX and holder. It’s ideal for in-vivo studies on adults and infants, sports and exercise assessments, as well as clinical studies and trials.

H2 optical probe

The H2 optode is designed for optimal performance in challenging environments. Its vertical illumination and retractable fiber tips enable accurate measurements even in the presence of hair. The flexible probe with adjustable interfiber distance ensures a secure fit on various head shapes. Ideal for in-vivo fNIRS studies, the H2 offers exceptional reliability.

S1 optical probe

The S1 optode is a compact and durable solution for easy fiber replacement, ideal for measurements on semi-planar surfaces. Its robust design makes it perfect for optical tissue characterization in both phantom and ex-vivo studies.

User-centric TD-NIRS data recording software

To ease your NIRS research, the TD-NIRS system is completed with a user-centric software platform designed for both research and clinical settings. It offers unparalleled flexibility with its 2-in-1 approach to NIRS data acquisition and analysis.

  • Research optimal interface

    Access multiple levels of TD-NIRS data depth, from live physiological parameters to raw photon time-of-flight distributions.

  • Tailored for clinicians

    Experience an optimized interface designed to streamline workflows in clinical environments.

NIRSBOX specifications

Continuous monitoring of absolute values

Time Domain Near Infrared Spectroscopy (TD-NIRS) is a non-invasive technique using low-power laser light to measure biomarkers, like brain function or muscle hemodynamics. Short light pulses (less than 200 ps) alter as they travel through tissue due to absorption and scattering. A sensitive photodetector reconstructs these pulses, and data processing allows the estimation of tissue absorption and scattering coefficients, which can indicate oxy- and deoxyhemoglobin concentrations.

TD-NIRS records the time each photon takes to travel through the sample, adding a new dimension to traditional NIRS. This timing helps determine the depth of photon penetration, enabling selective measurement of deep tissue changes while minimizing superficial and systemic influences.

Time Domain NIRS package

What's in the box?

  • NIRSBOX

  • Tissue mimicking phantom

  • USB cable

  • Power cable

  • Optical probe with necessary accessories

  • Contact sensor override plug

The NIRSBOX is intended to be used for research applications only.